Aldosterone and refractory hypertension
نویسندگان
چکیده
منابع مشابه
Essential hypertension and aldosterone.
MANY FACTORS have been implicated in the etiology of essential hypertension and at present the primary cause of this disease remains obscure. The relationship of sodium to the development of hypertension and the question of involvement of the adrenal cortex has been the subject of numerous investigations. Efforts by earlier investigators to show a hypersecretion of corticosteroids in this condi...
متن کاملUrinary aldosterone and hypertension.
A POSSIBLE ETIOLOGIC ROLE of the 18.1kadrenal cortex in the genesis of clinical hypertension has been recognized since Goldblatt's demonstration in 1937 that adrenalectomy prevents the expected development of hypertension following bilateral renal artery constriction.' Recently, interest in this possibility has been intensified by reports that some hypertensive patients excrete2-6 and secrete7 ...
متن کاملRefractory Hypertension
The term resistant hypertension has been used since the early 1960s to identify patients with difficult-to-treat hypertension, meaning mostly, resistance to pharmacological therapy. In the 5 decades since the term was seemingly first applied, resistant hypertension has been consistently defined as failure to control high blood pressure despite of use of ≥3 antihypertensive agents of different c...
متن کاملAldosterone secretion and primary and malignant hypertension.
After the synthesis of desoxycorticosterone (DOC), it became apparent that this corticosteroid, the physiological effects of which are concerned primarily with sodium and potassium metabolism, can produce a state of hypertension both in animals and in man (1, 2). The induced hypertension is dependent upon the administration of adequate amounts of dietary sodium, whereas the hypertensive state, ...
متن کاملRenin and aldosterone in essential hypertension.
1. The renin-aldosterone system was studied in seventy-one selected hypertensive patients. Nine (13%) were diagnosed as having primary aldosteronism. Ofthe twentythree patients who presented with a history of unprovoked hypokalaemia, the incidence of primary aldosteronism was 40%. 2. Renin and aldosterone responses to the combined stimuli of a low sodium diet and the upright posture were suppre...
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ژورنال
عنوان ژورنال: American Journal of Hypertension
سال: 2005
ISSN: 0895-7061
DOI: 10.1016/j.amjhyper.2005.03.646